While climate change is certain, precisely how climate will change is less clear. Breakthroughs in the accuracy of climate projections and in the quantification of their uncertainties are now within reach, thanks to advances in the computational and data sciences and in the availability of Earth observations from space and from the ground. Schneider will survey the design of a new Earth system model that the Climate Modeling Alliance (CliMA) is developing. The model exploits tools from machine learning and data assimilation jointly with process-informed models, with the goal of achieving a new level of accuracy in modeling important small-scale processes such as clouds and precipitation.